REPORT ON SASGO MEETING OF 28 NOVEMBER 2008 HELD
IN STELLENBOSCHSASGO ended 2008 on a
high note with a very successful meeting that was made
possible with generous sponsorship organised by one of
our members Dr George du Toit. The meeting was attended
by delegates from all over South Africa active in the
field of gynaecological oncology and the afternoon
session was attended by many pathologists with an
interest in cytology.
The day started with a
session on the effect of the HIV pandemic on cervical
cancer and HPV related disease and a number of excellent
talks were delivered by experts in the field of cervical
cancer. The first session was chaired by the emeritus
professor Ernie Sonnendecker who added significant depth
to the discussion because of his years of experience and
study in the field.

Prof E Sonnendecker adds
experience
The first talk given by Dr Mani
Moodley from the University of Kwa-Zulu Natal on
invasive cervical cancer in the HIV infected population,
focussed on the strong like between these two very
prevalent diseases in South Africa. His talk was
followed by a discussion about low-grade squamous
intra-epithelial lesions (LSIL) which is a common
occurrence in HIV positive patients. Dr Liz Hugo, from
Stellenbosch University, argued that HIV may alter the
well described course of pre-malignant disease and HIV
positive individuals progress quicker to invasive
disease and may need closer surveillance.
Dr
Arrie Mouton presented interesting data about surgery in
HIV positive patients and gave clear guidelines about
planning of major surgery in these patients.

From left to right: Prof I Loftus, I le Roux, Dr T
Erasmus, Prof G Dreyer, Dr A Mouton
Dr Msibi from
the University of Limpopo gave a good summary of the
basic science behind the interaction between HIV and HPV
infection and concluded that further surveillance and
research of the current epidemic of both HPV and HIV is
essential.
Prof Franco Guiddozzi from Wits
University ended the first morning session with a
discussion about the potential benefits of HPV
vaccination in the background of the HIV burden in South
Africa.
The second session of the morning was
chaired by Prof Hennie Cronjč from the University of the
Free State who published widely in the field of cervical
cancer prevention. The first talk in this session was by
Dr Hanna Simonds from Stellenbosch University about
treatment of advanced cervical cancer in HIV positive
patients. After careful study of the available
literature she concluded with recommendations that all
patients diagnosed with advanced cervical cancer should
be started on HAART therapy at the time of diagnosis
before starting with radiotherapy but warned that there
may be increased risks of toxicity in this sub-group of
patients.

Prof H Cronje chairs a session
Dr Bruce Howard from the University of Cape Town and
Dr Trudy Smith from Wits both gave background and
suggestions about the management of HPV related vulva
conditions. The severe morbidity associated with
extensive vulval Condylomata acuminate was clearly
demonstrated and suggestions about management were
discussed. The discussion after the two talks was lively
and highlighted the paucity of effective treatment
options available.

From left to right: Proff L
Denny, E Sonnendecker and Dr H Van der Merwe
After lunch the topic for discussion was a
mini-symposium on liquid-based cytology (LBC). The topic
was introduced by two pathologists Dr Judy Whittiker
from Cape Town and Dr Thomas Slavic from Pretoria who
interpreted the large body of medical literature on this
topic. Miss Irene le Roux added a very important
perspective from the public sector scenario.This was
followed by a lively discussion on the merits or not of
liquid-based cytology. This session was attended by many
pathologists both in the private and the public sector.

Dr Whittaker and Prof Lindeque in discussion
The conclusion of the LBC discussion will be
prepared in a consensus statement.
The day was
concluded with a SASGO Annual General Meeting at which
time the future planning for SASGO was discussed.
The next meeting will be at the same time as the O&G
update conference in Pretoria on 21-23rd May 2009.